Gregor Townsend has turned to Stuart Hogg to lead Scotland in the Six Nations following Greig Laidlaw's international retirement.
Aston Villa and Scotland are reportedly set to be without John McGinn for three months after he sustained an ankle fracture.
Former Scotland and Newcastle Falcons lock Doddie Weir has quickly proven a source of inspiration for Rob Burrow following his diagnosis.
Fly-half Greig Laidlaw said it was an "incredibly hard" decision to retire from international rugby.
After making 55 appearances in a six-year international career, Tommy Seymour has retired from Scotland duty.
John Barclay, a veteran of 76 caps, will continue his rugby career but has opted to step away from Scotland duty.
The Euro 2020 play-off draw took place on Friday, with Scotland to face Israel at Hampden Park in March's semi-finals.
Danny Wilson will replace Dave Rennie when the Glasgow Warriors head coach takes the Australia job.
South Africa can enjoy the status of world champions for the next four years and in 2020 will play matches with Scotland and Georgia.
Scotland went behind to a rasping effort from Baktiyor Zainutdinov on Tuesday, but John McGinn and Steven Naismith secured a comeback win.