Australia were heading for defeat in Graham Arnold's first home game back in charge before a dramatic late intervention against South Korea.
In a game that did not come to life until the final half-hour, it was South Korea who emerged victorious over Uruguay.
It is expected Luis Suarez will not play in Uruguay's games this month as he will be attending the birth of his third child.
Tuesday's friendly between South Korea and Chile in Suwon ended in a goalless draw after misses from Arturo Vidal and Diego Valdes.
A month after being sacked by Chongqing Dangdai Lifan, Paulo Bento has been appointed as the new coach of South Korea.
There was a shock at Helong Stadium as China condemned South Korea to a potentially damaging loss on the road to Russia 2018.