Manu Tuilagi has joined Sale Sharks for the 2020-21 season, so he will still be available for England selection.
England prop Joe Marler has received a 10-week suspension after a flashpoint involving Alun Wyn Jones in Saturday's clash with Wales.
Joe Marler and Courtney Lawes will face a disciplinary hearing on Thursday following incidents in the defeat of Wales.
Indiscipline again threatened to undermine Eddie Jones' England against Wales, but their capacity to thrill was also on display.
Eddie Jones has made four changes to the England starting line-up for the showdown with Ireland at Twickenham.
Eddie Jones says Manu Tuilagi should be fit to return against Ireland, while fellow centre Henry Slade will be monitored.
There was mixed news from head coach Eddie Jones for England on the injury front on Thursday.
Eddie Jones confirmed Manu Tuilagi will not face Scotland, but is hopeful the centre will take on Ireland at Twickenham.
In-form Harlequins number eight Alex Dombrandt will play no part in the Calcutta Cup clash after being left out of England's squad.
Manu Tuilagi, George Ford and Jonny May were all the subject of jibes from Matt Toomua ahead of the Australia's battle with England.