Mako Vunipola could play for Saracens this weekend, but England were advised not to take any risks following the prop's trip overseas.
Experienced duo Dan Biggar and Liam Williams are on course to be fit for Wales' showdown with England at Twickenham.
Ireland's clash with Italy in Dublin is the only Six Nations match to be postponed due to the coronavirus.
Fly-half Finn Russell will play no part in the Six Nations, but could make his Scotland return later this year.
The IRFU has confirmed the postponement of Ireland versus Italy in the interest of public health.
Absent for the opening three matches of the Six Nations, Anthony Watson is back in the mix for England this week.
Wales full-back Liam Williams has joined the Scarlets ahead of schedule, while Rhys Webb joined Bath ahead of a move to Ospreys.
Wales look highly unlikely to retain their Six Nations title after a loss to France, but Wayne Pivac felt they were hard done by.
France kept their Grand Slam hopes live with a famous win in Cardiff, but Romain Ntamack says they are not getting ahead of themselves.
Former France flanker Serge Betsen is looking forward to seeing Shaun Edwards' impact in evidence when Les Bleus take on Wales.