Fabinho's injury could mean opportuinities for the likes of Naby Keita, Adam Lallana and Xherdan Shaqiri, says Liverpool boss Jurgen Klopp.
Liverpool are closing in on a club record for top-flight games without defeat and Naby Keita does not expect his side to lose focus.
Joel Matip's troublesome knee injury is set to see him miss Liverpool's upcoming meeting with Manchester City.
Neco Williams made his senior debut and Harvey Elliott became the youngest Liverpool player to appear at Anfield as the Reds beat Arsenal.
Jurgen Klopp made five changes to his Liverpool side for the visit to Genk in the Champions League, including a return for Mohamed Salah.
Jurgen Klopp praised the way Liverpool rallied late in their 1-1 draw with Manchester United but questioned the hosts' opening goal.
Liverpool midfielder Naby Keita will be in the squad and prepared to play against his former side Salzburg in the Champions League.
Liverpool manager Jurgen Klopp shrugged off talk the European champions were back on their perch.
Liverpool's starting XI in the EFL Cup match against MK Dons could include Rhian Brewster and Caoimhin Kelleher, as well as Naby Keita.
Alisson is not expected to return to Liverpool action until next month but Naby Keita is nearing a comeback, according to Jurgen Klopp.