Jonny Bairstow, Sam Curran and Mark Wood have not been included in the England squad for the opening two Tests against India.
Batsman Bairstow, all-rounder Curran and paceman Wood have been rested and will fly home after the ongoing Test series in Sri Lanka along with quick Craig Overton.
Jofra Archer, Ben Stokes and Rory Burns are back in the squad for a series that starts at MA Chidambaram Stadium in Chennai on February 5.
Fast bowler Archer and all-rounder Stokes did not travel to Sri Lanka as they were given a break, while opening batsman Burns stayed at home for the birth of his first child.
Batsman Ollie Pope will fly out to India and be added to a 16-man squad when he has fully recovered from a shoulder operation.
The national selectors have also named six travelling reserves, three of which are spinners, for the series against an India side on a high from a dramatic 2-1 victory in Australia.
England squad for first two Tests against India:
Joe Root (captain), Jofra Archer, Moeen Ali, James Anderson, Dom Bess, Stuart Broad, Rory Burns, Jos Buttler, Zak Crawley, Ben Foakes, Dan Lawrence, Jack Leach, Dom Sibley, Ben Stokes, Olly Stone, Chris Woakes.
James Bracey, Mason Crane, Saqib Mahmood, Matt Parkinson, Ollie Robinson, Amar Virdi.