Joe Cokanasiga retains his starting berth for England's Cook Cup clash with Australia, while Dylan Hartley and Manu Tuilagi have been named among the replacements.
Cokanasiga scored a debut try in the victory over Japan last weekend and will start on the right wing on Saturday, with Jonny May coming in on the left flank as Chris Ashton and Jack Nowell miss out due to injury.
Jamie George gets the nod over co-captain Hartley, who is set to make a record 56th international appearance at Twickenham off the bench.
George Ford drops out of the side with Owen Farrell restored at fly-half to take skipper duties and scrum-half Ben Youngs regains the number nine shirt.
Henry Slade and Ben Te'o reunite in midfield, with Tuilagi in contention to win his first cap for well over two years after recovering from a groin strain.
Sam Underhill starts at openside flanker, so Mark Wilson moves to number eight and Brad Shields comes in at blindside flanker with Nathan Hughes having to settle for a place on the bench after serving a ban.
Eddie Jones shifts Courtney Lawes into the second row alongside Maro Itoje, while props Ben Moon and Kyle Sinckler are restored to the side.
England: Elliot Daly, Joe Cokanasiga, Henry Slade, Ben Te'o, Jonny May, Owen Farrell (co-captain) Ben Youngs; Ben Moon, Jamie George, Kyle Sinckler, Maro Itoje, Courtney Lawes, Brad Shields, Sam Underhill, Mark Wilson.
Replacements: Dylan Hartley (co-captain), Alec Hepburn, Harry Williams, Charlie Ewels, Nathan Hughes, Richard Wigglesworth, George Ford, Manu Tuilagi.