After dispatching Serena Williams in the quarter-finals, Shelby Rogers could not find a way past Jil Teichmann, who won comfortably.
Top seed Serena Williams was ousted 1-6 6-4 7-6 (7-5) by fellow American Shelby Rogers in Lexington on Friday.
American teenager Coco Gauff battled into the Top Seed Open quarter-finals.
Serena Williams will meet sister Venus for a 31st time after winning at the Top Seed Open.
The last WTA and ATP events took place in March, and tennis has been a chaotic sport during the lockdown of the two main tours.
Wimbledon has thrown up some of the great sporting drama, but the state of the world means we must wait until 2021 for the next instalment.
Patrick Mouratoglou says Coco Gauff is "just different" and has remarkable inner strength for someone of her age.
Coco Gauff, the 16-year-old US tennis rising star, delivered a powerful speech in Delray Beach, Florida, demanding social justice.
Sunday should have marked the start of the French Open, and its postponement hit home for players including Rafael Nadal and Coco Gauff.
Teenager Coco Gauff has felt the pressure of living up to high expectations, but she has not been diagnosed with depression.