England's Six Nations preparations have been impacted by a positive coronavirus test for assistant coach Matt Proudfoot.
Players including Chris Robshaw have been sanctioned for breaches of COVID-19 protocols in October.
Owen Farrell booted 14 points and could afford to miss a couple of kicks as Eddie Jones' England won comfortably enough in Wales.
The Rugby Football Union has charged 13 Barbarians players for breaching COVID-19 protocols which meant a match with England was cancelled.
Ben Youngs and Jamie George will win their 100th and 50th caps respectively when England take on Italy in their final Six Nations game.
Ben Youngs and Jamie George will achieve milestones for England in Saturday's Six Nations tussle with Italy in Rome.
England will be without some familiar faces for the Six Nations clash with Italy, with Eddie Jones including nine uncapped players.
Complications relating to coronavirus could see Eddie Jones lose three members of his England training squad.
Eddie Jones had a huge impact on former England flanker James Haskell, who admits he is still fearful of the Australian.
Head coach Eddie Jones says England's preparations for their decisive Six Nations clash with Italy start now.