Eddie Jones has included three uncapped players for his England squad for the Six Nations, which starts in February.
Rhys Webb was a notable absentee from Wales' Six Nations squad, but Dan Lydiate returns and the uncapped Josh Macleod has been included.
England's Six Nations preparations have been impacted by a positive coronavirus test for assistant coach Matt Proudfoot.
South Africa's director of rugby Rassie Erasmus says the world champions are prepared to go to "option Z" to ensure they face the Lions.
England open their Six Nations campaign against Scotland on February 6 - but Kyle Sinckler will not be available.
European club rugby is on hold after the French government prohibited Top 14 teams from playing in the Champions Cup and Challenge Cup.
Alun Wyn Jones, the most capped Test player of all time, expects to captain Wales in their first match of the Six Nations in Cardiff.
The ongoing COVID-19 situation has led to uncertainty over whether the British and Irish Lions will travel as planned.
Jake Ball will leave Wales next July and return to Australia, having not yet been able to meet his newborn baby.
Jerome Kaino knows the time will be right to end his playing days in 2021, but would like to stay at Toulouse in a coaching role.