A second knee operation will see Harvey Barnes miss the Premier League run-in, as well as the FA Cup final on May 15.
Leicester City beat Southampton 1-0 to reach their first FA Cup final in 52 years and Brendan Rodgers is now eyeing victory over Chelsea.
Kelechi Iheanacho's second-half goal was the difference as Leicester City booked an FA Cup final date against Chelsea.
Manchester City lost Kevin De Bruyne to injury and were eliminated from the FA Cup by Hakim Ziyech's winner for Chelsea at Wembley.
Chelsea overcame Manchester City 1-0 at Wembley on Saturday to reach the FA Cup final for the fourth time in five seasons.
Tests will be carried out on Kevin De Bruyne's ankle injury on Sunday but Manchester City boss Pep Guardiola is not optimistic.
Manchester City could end the season with a trio of titles but may yet again need to take on Thomas Tuchel and Chelsea, victors on Saturday.
Kevin De Bruyne gave Manchester City cause for concern as he had to be substituted against Chelsea on Saturday.
Chelsea boss Thomas Tuchel allowed his players to have a glass of wine or a beer after choosing to remain in Spain in midweek.
Raheem Sterling has been a peripheral figure for Manchester City of late but remains a "key" player for the club.