Five-time finalist Andy Murray will not compete at the Australian Open after failing to arrange a "workable quarantine" with authorities.
Brazilian Carlos Bernardes is recovering in a Melbourne hospital after suffering a reported heart attack before the year's first grand slam.
World number one Novak Djokovic said his good intentions in trying to help out his fellow players in Melbourne have been "misconstrued."
Two-time Australian Open champion Victoria Azarenka pleaded for players to be more understanding.
World number 13 Roberto Bautista Agut compared being in hotel quarantine to imprisonment.
Australian Open tournament director Craig Tiley discussed Novak Djokovic's reported requests.
Players self-isolating ahead of the Australian Open have been told they will not get "special treatment" despite complaints over conditions.
There are now 72 players in total quarantining ahead of the Australian Open, leaving the tournament in crisis.
A host of players must stay in their hotel rooms for 14 days, but the Australian Open chief says the tournament will not be postponed.
After three COVID-19 positives across two charter flights to Melbourne, a host of leading tennis stars are entering hard lockdown.