Daryn Dupavillon and Ottniel Baartman could make their Test debuts during South Africa's two-match Test series in Pakistan.
South Africa clinched a 2-0 series win over Sri Lanka on Tuesday, as they took the second Test by 10 wickets in Johannesburg.
The onus is on the captain to put Sri Lanka in a position to win after he sparked a revival from the tourists in Johannesburg.
Dean Elgar became the 10th South African to reach 4,000 Test runs as the Proteas overwhelmed Sri Lanka on day one.
The ongoing COVID-19 situation has led to uncertainty over whether the British and Irish Lions will travel as planned.
Sri Lanka will be without a number of key players due to injury for the second and final Test of the series against South Africa.
Royal Challengers Bangalore will not have South Africa great Dale Steyn in their ranks for this year's Indian Premier League.
After Faf du Plessis posted 199 on day three, South Africa seized control and finished up as emphatic first Test winners against Sri Lanka.
South Africa are in a strong position at the close of play on day three of the first Test with Sri Lanka thanks to 199 from Faf du Plessis.
Paceman Kagiso Rabada is back in contention for the second Test between South Africa and Sri Lanka.